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Index > Protein center > Matk(Gene name) > Mouse
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  • Matk (Gene name),
  • Megakaryocyte-associated tyrosine-protein kinase (Protein name ),  MATK_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Matk(Ctk;Ntk);
    Protein name:
    Megakaryocyte-associated tyrosine-protein kinase;
    Alternative:
    Tyrosine-protein kinase CTK;Protein kinase NTK;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with KIT.
    Function:
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    505
    Sequence:
    50:
    MARRSSRVSW | LAFEGWESRD | LPRVSPRLFG | AWHPAPAAAR | MPTRWAPGTQ | 
    100:
    CMTKCENSRP | KPGELAFRKG | DMVTILEACE | DKSWYRAKHH | GSGQEGLLAA | 
    150:
    AALRHGEALS | TDPKLSLMPW | FHGKISGQEA | IQQLQPPEDG | LFLVRESARH | 
    200:
    PGDYVLCVSF | GRDVIHYRVL | HRDGHLTIDE | AVCFCNLMDM | VEHYTKDKGA | 
    250:
    ICTKLVKPRR | KQGAKSAEEE | LAKAGWLLDL | QHLTLGAQIG | EGEFGAVLQG | 
    300:
    EYLGQKVAVK | NIKCDVTAQA | FLDETAVMTK | LQHRNLVRLL | GVILHHGLYI | 
    350:
    VMEHVSKGNL | VNFLRTRGRA | LVSTSQLLQF | ALHVAEGMEY | LESKKLVHRD | 
    400:
    LAARNILVSE | DLVAKVSDFG | LAKAERKGLD | SSRLPVKWTA | PEALKNGRFS | 
    450:
    SKSDVWSFGV | LLWEVFSYGR | APYPKMSLKE | VSEAVEKGYR | MEPPDGCPGS | 
    500:
    VHTLMGSCWE | AEPARRPPFR | KIVEKLGREL | RSVGVSAPAG | GQEAEGSAPT | 
    505:
    RSQDP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    E15358m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    E15358r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    E15358h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    U15358r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    U15358h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    U15358m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    P15358Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    P15358Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Cat.:
    P15358Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Monoclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Monoclonal Antibody for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Protein for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Protein for Mouse Megakaryocyte-associated tyrosine-protein kinase
    Protein for Mouse Megakaryocyte-associated tyrosine-protein kinase

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family."
      Klages S. , Adam D. , Class K. , Fargnoli J. , Bolen J.B. , Penhallow R.C.
      Proc. Natl. Acad. Sci. U.S.A.91:2597-2601(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Brain.
    2. 2.
      "Ntk: a Csk-related protein-tyrosine kinase expressed in brain and T lymphocytes."
      Chow L.M.L. , Jarvis C.D. , Hu Q. , Nye S.H. , Gervais F.G. , Veillette A. , Matis L.A.
      Proc. Natl. Acad. Sci. U.S.A.91:4975-4979(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
      tissue: Thymus.
    3. 3.
      "Presence of alternative 5' untranslated sequences and identification of cells expressing ctk transcripts in the brain and testis."
      Kaneko Y. , Nonoguchi K. , Fukuyama H. , Takano S. , Higashitsuji H. , Nishiyama H. , Takenawa J. , Nakayama H. , Fujita J.
      Oncogene10:945-952(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      strain: DDY/STD.
    4. 4.
      "Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene."
      Chow L.M. , Davidson D. , Fournel M. , Gosselin P. , Lemieux S. , Lyu M.S. , Kozak C.A. , Matis L.A. , Veillette A.
      Oncogene9:3437-3448(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-43 (ISOFORM 1);ALTERNATIVE SPLICING;SUBCELLULAR LOCATION
      strain: 129/Sv.
      tissue: Kidney.
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